What is the net result of lost tone in blood vessels during distributive shock?

The net result of lost tone in blood vessels during distributive shock is indeed hypoperfusion of tissues. Distributive shock occurs when blood vessels widen, which can happen due to conditions like sepsis, anaphylaxis, or neurogenic shock. When blood vessels lose their tone, the vascular capacity increases, leading to a decrease in systemic vascular resistance. This causes a reduced venous return to the heart and subsequently a drop in cardiac output.

As blood flow becomes less effective, tissues do not receive adequate oxygen and nutrients, leading to hypoperfusion. This situation can result in cellular injury or death due to lack of essential supplies, highlighting the critical nature of maintaining vascular tone and blood pressure to ensure proper perfusion throughout the body's tissues. In this context, the other options do not account for the physiological impact of losing vascular tone and its direct consequence on tissue perfusion.